Dr. Melaxin is a South Korean dermocosmetic brand built around a slow aging philosophy and run by CEO Yu Kyoung Hwa. Its formulas are notified by South Korea's Ministry of Food and Drug Safety and organized into distinct lines for exfoliation, firmness, dark spots and pore care. Here is what the Peel Shot, Calcium and TX products below are each meant to do.

Dr. Melaxin Explained: Peel Shots, Calcium And TX Lines
What Dr. Melaxin actually is
Aristotle, writing in the fourth century BC, spent a surprising number of pages on sponges. In his History of Animals he notes that they grow on rocks and feed on slime, sorts them into three kinds, and gives the finest, closest-textured and strongest one a nickname: the sponge of Achilles. Elsewhere he could not quite decide whether sponges were animals or plants. Two thousand years later, sponge is still doing surprising work, and one Korean brand has turned it into a skincare idea.
Dr. Melaxin is a South Korean dermocosmetic brand under Brand501 Corp, founded in 2021 around what it calls a slow aging philosophy. CEO Yu Kyoung Hwa describes the approach herself in the brand's launch materials. The products are notified by South Korea's Ministry of Food and Drug Safety, and the brand follows an 8-FREE standard that leaves out PEGs, mineral oil and artificial fragrance. The name comes from medical vaccine, which tells you where it wants to sit: closer to the clinic than the spa. I like that it is clear about its lane, even if it is a busy lane.
The trick is to see the Peel Shot line as the front door, because the marine sponge idea lives here: the brand uses bio-spicule technology derived from marine sponges to exfoliate. The Black Rice Ampoule and the White Rice Ampoule are the starting pair, depending on how much brightening you want alongside the exfoliating. The Kojic Acid Turmeric Serum and Spray, the TX-Serum and TX-Spray, and the Glow White Rice Serum and Toner are the lighter, more frequent versions of the same thought.

The Peel Shot line

Peel Shot Exfoliating Black Rice Ampoule
Dr. Melaxin

Peel Shot Exfoliating White Rice Ampoule
Dr. Melaxin

Peel Shot Exfoliating Kojic Acid Turmeric Serum
Dr. Melaxin

Peel Shot Exfoliating Kojic Acid Turmeric Spray
Dr. Melaxin

Peel Shot Exfoliating TX-Serum
Dr. Melaxin

Peel Shot Exfoliating TX-Spray
Dr. Melaxin

Peel Shot Glow White Rice Serum
Dr. Melaxin

Peel Shot Glow White Rice Toner
Dr. Melaxin
Face serums, creams and balms
Start with the sequence, not the shopping list. The brand designs its Calcium Volume Multi Balm as an aftercare step to use right after a Peel Shot ampoule, so if you are buying both, that is the order to learn first.
The Cemenrete Calcium line is the firmness story, built on a calcium peptide complex with hydrolyzed elastin, niacinamide, ceramides and hyaluronic acid. It comes as the Calcium Volume Serum, the Calcium Volume Cream and the Multi Balm, a stick you can keep on a vanity and tap over the day. I would treat the balm as the finish and the serum and cream as the daily layers. The Cyano Pink Spicule Serum and Cream carry the bio-spicule idea into a richer, more cushioned texture. The Picotonic Shot Pigmentation Serum and Cream go after dark spots instead of firmness, so choose based on the thing you see in the mirror. The Facephalt Tightening Cream is the one built purely around a taut, lifted feel.
A pairing I like: the Calcium Volume Serum under the Calcium Volume Cream, then the balm on top, for one line that behaves like a small system.
What I would skip: stacking pigmentation and tightening creams in one morning. Choose the concern that bothers you and give it a few weeks.

Calcium Volume Serum
Dr. Melaxin

Calcium Volume Cream
Dr. Melaxin

Calcium Volume Multi Balm
Dr. Melaxin

Cyano Pink Spicule Serum
Dr. Melaxin

Cyano Pink Spicule Cream
Dr. Melaxin

Picotonic Shot Pigmentation Serum
Dr. Melaxin

Picotonic Shot Pigmentation Cream
Dr. Melaxin

Facephalt Tightening Cream
Dr. Melaxin

Eye, neck and lip treatments
One rule for the parts of the face people forget: give them their own product. Dr. Melaxin treats the eyes, neck and lips as separate categories, which I think is the smartest thing about the range.
Around the eyes, the Eyephalt Eyebag Cream takes on puffiness and the TX Retinalsome Double Effect Eye Cream goes after fine lines. The Calcium Dark Spot Cover Eye Cream and the Calcium Volume Eye Patch bring the calcium peptide story down from the face line. I would keep the patches for the morning of something important. On the neck, the Necklinephalt Neck Cream and the Necksphalt ECM Ceramide Neck Serum put the firming logic where most routines simply stop. It is a good place to be consistent, since the neck shows up in every photo and every video call.
The BP line brings the bio-spicule idea to the lips with the BP Spicule Plumping Lip Shot, in Maxi and Mild strengths depending on how much sensation you want. Begin with Mild, and let the lip skin tell you whether it wants more.
What I would skip: the Maxi lip shot right before a long day of talking. Try new lip products on a quiet evening first.

Eyephalt Eyebag Cream
Dr. Melaxin

TX Retinalsome Double Effect Eye Cream
Dr. Melaxin

Calcium Dark Spot Cover Eye Cream
Dr. Melaxin

Calcium Volume Eye Patch
Dr. Melaxin

Necklinephalt Neck Cream
Dr. Melaxin

Necksphalt ECM Ceramide Neck Serum
Dr. Melaxin

BP Spicule Plumping Lip Shot Maxi
Dr. Melaxin

BP Spicule Plumping Lip Shot Mild
Dr. Melaxin

Brightening TX, hydrating Aqua Ion and the cleansers
A tip for any brightening routine: wear your sunscreen the next morning, every time. Brightening products and forgotten sunscreen are a bad pair, and no ampoule fixes that.
The TX line is Dr. Melaxin's answer to dark spots, and this grid gives it a full routine. The TX-Astaxanthin Triple Brightening Jelly Serum, the TX-Cream, the TX-Serum and the TX-Peeling Toner can be layered or used one at a time, depending on how much brightening you want. If you are new, begin with the TX-Serum and add the cream once skin is settled.
Underneath, the Aqua Ion line handles plain water. The Aqua Ion Plasma Water Glow Ampoule and the Plasma Hydrating Gel Cream sit well under either TX or Calcium, and I would think of them as the calm days between the active ones. The Melting Cleanser and the TX-Serum Cleanser bookend the routine, washing off makeup and sunscreen before any of the treatment steps start.
A pairing I like: the Melting Cleanser at night, the Aqua Ion ampoule after it, and a TX serum only on the evenings skin feels steady.
What I would skip: the TX-Peeling Toner and a Peel Shot ampoule on the same night. Give skin a day between exfoliating steps.
How I would actually build a Dr. Melaxin routine
I think the line makes the most sense when you pick one lane and commit. Peel Shot, Calcium, TX, BP and the eye and neck treatments are each built to work as their own small system, so choose a Peel Shot ampoule a few times a week for dullness, or a TX serum if dark spots come first. Add the Calcium Multi Balm or the Aqua Ion ampoule once you know which base you like.
Buy from an authorized retailer, since the brand's fast growth on TikTok Shop has attracted lookalike sites. Aristotle only had to describe the sponge. You have to be careful where you click. If you want to keep browsing, I also put together Celimax Skincare Explained and Dr. Squatch.













